The microbiome(s) and cancer: know thy neighbor(s)

Share with Thy Neighbors

Peer to peer (P2P) systems are traditionally designed to scale to a large number of nodes. However, we focus on scenarios where the sharing is effected only among neighbors. Localized sharing is particularly attractive in scenarios where wide area network connectivity is undesirable, expensive or unavailable. On the other hand, local neighbors may not offer the wide variety of objects possible ...

Know Thy Participant 1 Running Head: KNOW THY PARTICIPANT Know Thy Participant: The Trouble with Nomothetic Assumptions in Moral Psychology

Know thy enemy

We recently described hypoxia as one of the leading mechanism for the recruitment of regulatory T cells (Treg) through CCL28 chemokine in ovarian cancer. Treg promote progression of cancer through tumor-specific immune paralysis but also reprogramming of angiogenesis. We review these mechanisms and discuss the challenges and opportunities for therapy targeting Treg.

Know Thy Toucher

Most of current academic and commercial surface computing systems are capable of multitouch detection and hence allow simultaneous input from multiple users. Although there are so far only few applications in this area which rely on identifying the user, we believe that the association of touches to users will become an essential feature of surface computing as applications mature, new applicat...

Brain, Know Thy Transcriptome, Know Thyself

In this issue of Neuron, Konopka et al. (2012) describe their comparison of transcriptomes from frontal pole, caudate nucleus, and hippocampus of multiple adult humans, chimpanzees, and rhesus monkeys. The data provide an initial opportunity for linking genomic and brain differences among these primate species.